The Adler Planetarium & Astronomy Museum in Chicago features the first planetarium built in the Western Hemisphere. The Adler is home to more than 35,000 square feet of exhibits, rrom scale models of the Solar System, to ancient astronomical instruments, to interactive adventures. The Adler is the only museum in the world with two full-size planetarium theaters which feature a variety of shows.

The Field Museum was founded to house the biological and anthropological collections assembled for the World's Columbian Exposition of 1893. Includes a world-class natural history library of more than 250,000 volumes. The Field Museum is the permanent home of Sue, the world's largest, most complete Tyrannosaurus rex.

Exhibits include Asian art, European paintings, armor, textiles, African and American Indian art, and modern/comtemporary art. Also features special exhibits.

Chicago Children’s Museum is a place where families and caregivers with infants and children are encouraged to create, explore, and discover together through play. The museum features three vibrant floors of exhibits and activities that provide sensory experiences and engaging educational content focusing on literacy, science, math, visual and performing arts, and health. Some of CCM's most popular exhibits include: Dinosaur Expedition, where kids can dig for dinosaur bones in an authentic excavation pit; WaterWays, an interactive system of pulleys, pumps, and pipes showcasing the wonders of water; Kids Town, an early-learning exhibit featuring a real CTA bus, mini-grocery store and kid-sized cityscape; daily free family art workshops in the Kraft Artabounds Studio; Pritzker Playspace, an area designed specifically for babies, toddlers, preschoolers, and their parents; Play It Safe, a realistic firehouse and fire truck that invites families to learn about fire safety through play; and Skyline, a National Science Foundation-funded exhibit that explores the science, engineering, art, and technology that keep Chicago's tallest buildings standing.

The Association of Children’s Museums (ACM) is a professional member service organization for the children’s museum field. ACM is the only organization representing museums and professionals dedicated to early childhood play, the starting point in the continuum of lifelong learning. The Association promotes the impact children’s museums have in preparing children for school, building 21st century skills and nurturing a love for lifelong learning.